Lisa Edelstein

From her introduction to television as Lisa E on MTV’s “Awake on the Wild Side” to her current role as “Dr. Lisa Cuddy” on HOUSE, Lisa Edelstein is no stranger to fearless roles. In the last several years, Edelstein has portrayed Rob Lowe’s call-girl girlfriend on “The West Wing,” the transsexual boyfriend of James LeGros on “Ally McBeal,” David Conrad’s lesbian sister on “Relativity” and an Orthodox Jew losing custody of her child on “Family Law.” Edelstein was again tapped by David E. Kelley, this time to play James Spader’s love interest on “The Practice.”

Additional television credits include her series regular role on “Leap of Faith” and guest turns on “Seinfeld,” “Without a Trace,” “Frasier” and “ER.” Edelstein also works extensively in the realm of voiceover, most recently as “Mercy Graves” on the animated “Superman” and “Justice League” series.

In feature films, Edelstein starred as Ben Stiller’s aerobics-obsessed date in “Keeping the Faith,” directed by Edward Norton. Additional credits include Mel Gibson’s “What Women Want,” “Daddy Day Care” with Eddie Murphy, “As Good As It Gets,” and the comedies “Say Uncle” and “Grilled” with Ray Romano and Kevin James. She also starred in the dramatic cable feature “Fathers and Sons” opposite Gale Harold.

Edelstein lives in Los Angeles in a century-old home with her cat and rescue dog. She is an avid practitioner of Ashtanga Yoga and volunteers her time by working with the Best Friends Animal Sanctuary.